| Division Two | |||
| 30/08/2000 | Berry Brow Lib | 0 - 4 | Netherton |
| 06/09/2000 | Netherton | 1 - 2 | Lindley Liberal |
| 09/09/2000 | Scholes | 0 - 1 | Netherton |
| 23/09/2000 | Scissett | 2 - 2 | Netherton |
| 30/09/2000 | Netherton | 3 - 0 | New Mill 94 |
| 07/10/2000 | Hepworth Utd | 2 - 0 | Netherton |
| FA Challenge Cup Round One | |||
| 21/10/2000 | Netherton | 6 - 4 | Parish Pump (WL) |
| 11/11/2000 | Mount | 1 - 1 | Netherton |
| 25/11/2000 | Storthes Hall | 3 - 2 | Netherton |
| 02/12/2000 | Netherton | 0 - 1 | Heywood Sports |
| 09/12/2000 | Netherton | 3 - 2 | Mount |
| FA Challenge Cup Round Two | |||
| 16/12/2000 | Netherton | 6 - 1 | Feney Bridge FC |
| 23/12/2000 | Netherton | 5 - 1 | Lepton Highlanders |
| 06/01/2001 | Lindley Liberal | 0 - 2 | Netherton |
| Barlow Cup Round Two | |||
| 13/01/2001 | Netherton | 1 - 2 | Hepworth Utd |
| FA Challenge Cup Round Three | |||
| 20/01/2001 | Sovereign Sports | 0 - 5 | Netherton |
| 27/01/2001 | Netherton | 5 - 0 | Scholes |
| 03/02/2001 | Marsden | 2 - 1 | Netherton |
| 17/02/2001 | Uppermill | 0 - 2 | Netherton |
| 10/03/2001 | Netherton | 5 - 2 | Marsden |
| 17/03/2001 | Netherton | 1 - 1 | Hepworth Utd |
| 24/03/2001 | Diggle | 2 - 1 | Netherton |
| FA Challenge Cup Round Four Quarter Final | |||
| 31/03/2001 | Kirkburton | 0 - 2 | Netherton |
| 05/04/2001 | Lepton Highlanders | 1 - 1 | Netherton |
| 07/04/2001 | Netherton | 5 - 1 | Berry Brow Lib |
| 12/04/2001 | Netherton | 2 - 0 | Diggle |
| 14/04/2001 | Netherton | 1 - 0 | Scissett |
| FA Challenge Cup Semi Final | |||
| 20/04/2001 | Netherton | P - P | Brackenhall Utd |
| 01/05/2001 | Netherton | 0 - 0 | Uppermill |
| 01/05/2001 | New Mill 94 | 0 - 0 | Netherton |
| 01/05/2001 | Netherton | 0 - 0 | Storthes Hall |
| 01/05/2001 | Heywood Sports | 0 - 0 | Netherton |